Center for the Study of Complex Malaria in India

Some of the research projects we have undertaken as part of the CSCMi include:

1. Describing the epidemiology of P. vivax and P. falciparum in India
   van Eijk AM et al. What is the value of reactive case detection in malaria control? A case-study in India and a systematic review. Malar J. 2016  Feb 6;15(1):67.

   Laishram DD et al. The complexities of malaria disease manifestations with a focus on asymptomatic malaria. Malar J 2012, 11:29.

   Kar NP et al. A review of malaria transmission dynamics in forest ecosystems. Parasit Vectors. 2014 Jun 9;7(1):265.

2. Identifying key elements of vector transmission in India van Eijk AM et al. The use of mosquito repellents at three sites in India with declining malaria transmission: surveys in the community and clinic. Parasit Vectors. 2016 Jul 27;9(1):418.

   Waite JL, Swain  et al. Increasing the potential for malaria elimination by targeting zoophilic vectors. Sci Rep. 2017 Jan 16;7:40551.

   Thomas S et al. Overhead tank is the potential breeding habitat of Anopheles stephensi in an urban transmission setting of Chennai, India. Malar J. 2016 May 11;15(1):274.

3. Describing the genomic epidemiology of P. vivax and P. falciparum in India and globally: Neafsey DE et al. The malaria parasite Plasmodium vivax exhibits greater genetic diversity than Plasmodium falciparum. Nat Genet. 2012 Sep;44(9):1046-50.

   Hupalo DN et al. Population genomics studies identify signatures of global dispersal and drug resistance in Plasmodium vivax. Nat Genet. 2016 Aug;48(8):953-8.

4. Developing methods and monitoring Plasmodium drug resistance in India: Mideo N at al. Ahead of the curve: next generation estimators of drug resistance in malaria infections. Trends Parasitol. 2013 Jul;29(7):321-8.

   Mideo N et al. A deep sequencing tool for partitioning clearance rates following antimalarial treatment in polyclonal infections. Evol Med Public Health.

   Rao PN et al. A Method for Amplicon Deep Sequencing of Drug Resistance Genes in Plasmodium falciparum Clinical Isolates from India. J Clin Microbiol. 2016 Jun;54(6):1500-11.

5. Characterizing the host immune response to malaria parasites in India: Uplekar S et al. Characterizing Antibody Responses to Plasmodium vivax and Plasmodium falciparum Antigens in India Using Genome-Scale Protein Microarrays. PLoS Negl Trop Dis. 2017 Jan 24;11(1):e0005323.

6. Studying the pathogenesis of cerebral malaria in India:
   Mohanty S et al. Magnetic resonance imaging during life: the key to unlock cerebral malaria pathogenesis? Malar J. 2014 Jul 18;13(1):276.

   Mohanty S et al. Magnetic Resonance Imaging of Cerebral Malaria Patients Reveals Distinct Pathogenetic Processes in Different Parts of the Brain. mSphere. 2017 Jun 7;2(3).

Full list of publications (pdf) >>

• Community Welfare Society Hospital, Rourkela, India
• Indian Institute of Public Health-Shillong, Meghalya, India
• Ispat General Hospital, Rourkela, India
• Jawaharlal Nehru University, Delhi, India.
• London School of Hygiene & Tropical Medicine, London, UK
• National Institute for Research on Tribal Health/Indian Council of Medical Research, Jabalpur, India
• Seattle Children's Research Institute, Seattle, USA
• University of Manchester

• The Pennsylvania State University, USA
• National Institute for Malaria Research/Indian Council of Medical Research, New Delhi, India

• International Center of Excellence for Malaria Research background
• Center for the Study of Complex Malaria in India NIH web pages

Essential Qualifications: Degree/Diploma in Nursing from a registered council of India.

Desirable Experience: 1 years of experience in ICU and prior knowledge of working with severe malaria patients. Candidates with experience of working in research projects/trials with knowledge of patient CRF filling will be preferred. Fluency in communication of English is highly desirable.

Essential Qualifications: Degree/Diploma in Nursing from a registered council of India.

Desirable Experience: 1 years of experience in ICU and prior knowledge of working with severe malaria patients. Candidates with experience of working in research projects/trials with knowledge of patient CRF filling will be preferred. Fluency in communication of English is highly desirable.

Essential Qualifications: Bachelor Degree in Science (B.Sc. Physics/ Chemistry/ Biology) with Diploma in Medical Laboratory Technology (DMLT) from a recognized Indian Institute.

Desirable Experience: 1 year of experience in biological samples (Blood/plasma/CSF) processing and preservationmethods. Training in Malaria microscopy foridentification of malaria parasite & DNA/RNA extraction technique is desirable. Sound knowledge of MS Excel for sample cataloguing, repository maintenance is preferrable for this post.